Article
Crosstalk between B cells and neutrophils in rheumatoid arthritis.
Immunology - 1 Dec 2021
Karmakar Utsa, Vermeren Sonja
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease without known cure that primarily affects synovial joints. RA has a prevalence of approximately 1% of the population worldwide. A vicious circle between two critical immune cell types, B cells and neutrophils, develops and promotes disease. Pathogenic anti-citrullinated protein antibodies (ACPA) directed against a range of citrullinated epitopes...
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