Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression.

doi:10.1371/journal.pone.0248254

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Article

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression.

PloS one - 1 Jan 2021

Martin Joanna, Asjadi Kimiya, Hubbard Leon, Kendall Kimberley, Pardiñas Antonio F, Jermy Bradley, Lewis Cathryn M, Baune Bernhard T, Boomsma Dorret I, Hamilton Steven P, Lucae Susanne, Magnusson Patrik K, Martin Nicholas G, McIntosh Andrew M, Mehta Divya, Mors Ole, Mullins Niamh, Penninx Brenda W J H, Preisig Martin, Rietschel Marcella, Jones Ian, Walters James T R, Rice Frances, Thapar Anita, O'Donovan Michael

Abstract excerpt

Anxiety and depression are common mental health disorders and have a higher prevalence in females. They are modestly heritable, share genetic liability with other psychiatric disorders, and are highly heterogeneous. There is evidence that genetic liability to neurodevelopmental disorders, such as attention deficit hyperactivity disorder (ADHD) is associated with anxiety and depression, particularly in females. We...

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PMID: 34473692
DOI: 10.1371/journal.pone.0248254
PMCID: PMC8412369

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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