Article
A new Trypanosoma cruzi genotyping method enables high resolution evolutionary analyses.
Memorias do Instituto Oswaldo Cruz - 1 Jan 2021
Probst Christian Macagnan, Melo Myllena de Fátima Alheiros Dias, Pavoni Daniela Parada, Toledo Max Jean de Ornelas, Galdino Tainah Silva, Brandão Adeilton Alves, Britto Constança, Krieger Marco Aurelio
Abstract excerpt
BACKGROUND: Trypanosoma cruzi is an important human pathogen in Latin America with nearly seven million people infected. It has a large degree of genetic diversity, classified into six discrete typing units (DTUs), which probably influences its physiological behavior and clinical manifestations. Several genotyping methods are available, with distinct performance on easiness, cost, resolution and applicability; no...
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