Article
Genome-scale multilocus microsatellite typing of Trypanosoma cruzi discrete typing unit I reveals phylogeographic structure and specific genotypes linked to human infection.
PLoS pathogens - 1 May 2009
Llewellyn Martin S, Miles Michael A, Carrasco Hernan J, Lewis Michael D, Yeo Matthew, Vargas Jorge, Torrico Faustino, Diosque Patricio, Valente Vera, Valente Sebastiao A, Gaunt Michael W
Abstract excerpt
Trypanosoma cruzi is the most important parasitic infection in Latin America and is also genetically highly diverse, with at least six discrete typing units (DTUs) reported: Tc I, IIa, IIb, IIc, IId, and IIe. However, the current six-genotype classification is likely to be a poor reflection of the total genetic diversity present in this undeniably ancient parasite. To determine whether epidemiologically important...
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