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Article

Genetic structure of Trypanosoma cruzi in Colombia revealed by a High-throughput Nuclear Multilocus Sequence Typing (nMLST) approach.

BMC genetics - 30 Sept 2013

Ramírez Juan David, Tapia-Calle Gabriela, Guhl Felipe

Abstract excerpt

BACKGROUND: Chagas disease is a systemic pathology caused by Trypanosoma cruzi. This parasite reveals remarkable genetic variability, evinced in six Discrete Typing Units (DTUs) named from T. cruzi I to T. cruzi VI (TcI to TcVI). Recently newly identified genotypes have emerged such as TcBat in Brazil, Colombia and Panama associated to anthropogenic bats. The genotype with the broadest geographical distribution...

Topics

Alleles
Chagas Disease
Cluster Analysis
Colombia
Gene Frequency
Genetic Variation
Genome, Helminth
Genotype
Humans
Linkage Disequilibrium
Multilocus Sequence Typing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Phylogeny

Recombination, Genetic

Trypanosoma cruzi

Source

Open in PubMed Open full text

Identifiers

PMID: 24079755
DOI: 10.1186/1471-2156-14-96
PMCID: PMC3850472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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