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Patients with systemic sclerosis show phenotypic and functional defects in neutrophils

1 Sept 2021

Abstract excerpt

BACKGROUND: Systemic sclerosis (SSc) is a multiorgan autoimmune disease characterized by inflammation, vascular modification, and progressive fibrosis of the skin and several visceral organs. Innate and adaptive immune cells, including myeloid, B and T cells, are believed to be central to the pathogenesis of SSc. However, the role and functional state of neutrophil granulocytes (neutrophils) are ill-defined in...

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PMID: 34467524
DOI: 10.1111/all.15073

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