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Article

Distinct functionality of neutrophils in multiple sclerosis and neuromyelitis optica.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Feb 2016

Hertwig Laura, Pache Florence, Romero-Suarez Silvina, Stürner Klarissa H, Borisow Nadja, Behrens Janina, Bellmann-Strobl Judith, Seeger Bibiane, Asselborn Natascha, Ruprecht Klemens, Millward Jason M, Infante-Duarte Carmen, Paul Friedemann

Abstract excerpt

BACKGROUND: In contrast to multiple sclerosis (MS), lesions in neuromyelitis optica (NMO) frequently contain neutrophils. However, the phenotypic profile of neutrophils in these two distinct pathologies remains unknown. OBJECTIVE: Our aim is to better understand the potential contribution of neutrophils to NMO and MS pathology. METHODS: We performed the first functional analysis of blood neutrophils in NMO and...

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Identifiers

PMID: 26540731
DOI: 10.1177/1352458515586084

Genes

TLR2
CXCR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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