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3D assessment of intervertebral disc degeneration in zebrafish identifies changes in bone density that prime disc disease

31 Aug 2021

Abstract excerpt

Back pain is a common condition with a high social impact and represents a global health burden. Intervertebral disc disease (IVDD) is one of the major causes of back pain; no therapeutics are currently available to reverse this disease. The impact of bone mineral density (BMD) on IVDD has been controversial, with some studies suggesting osteoporosis as causative for IVDD and others suggesting it as protective...

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PMID: 34465741
DOI: 10.1038/s41413-021-00156-y

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