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Article

Decoding the intervertebral disc: Unravelling the complexities of cell phenotypes and pathways associated with degeneration and mechanotransduction.

Seminars in cell & developmental biology - 1 Feb 2017

Kerr Geoffrey J, Veras Matthew A, Kim Min Kyu M, Séguin Cheryle A

Abstract excerpt

Back pain is the most common cause of pain and disability worldwide. While its etiology remains unknown, it is typically associated with intervertebral disc (IVD) degeneration. Despite the prevalence of back pain, relatively little is known about the specific cellular pathways and mechanisms that contribute to the development, function and degeneration of the IVD. Consequently, current treatments for back pain...

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Source

Identifiers

PMID: 27208724
DOI: 10.1016/j.semcdb.2016.05.008

Genes

IVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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