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Developmental mechanisms of intervertebral disc and vertebral column formation

18 Jul 2017

Abstract excerpt

The vertebral column consists of repeating units of ossified vertebrae that are adjoined by fibrocartilagenous intervertebral discs. These structures form from the embryonic notochord and somitic mesoderm. In humans, congenital malformations of the vertebral column include scoliosis, kyphosis, spina bifida, and Klippel Feil syndrome. In adulthood, a common malady affecting the vertebral column includes disc...

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PMID: 28719048
DOI: 10.1002/wdev.283

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