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Article

Genotyping of paired KPC-producing Klebsiella pneumoniae isolates with and without divergent polymyxin B susceptibility profiles.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] - 1 Dec 2021

Sampaio Suely Carlos Ferreira, Bigelli Carvalho Rozane de Lima, Mimica Marcelo Jenné, da Silva Cely Barreto, Mimica Lycia Mara Jenné, de Lima Aline Valerio, Lima Keila de Oliveira, Rocha Darlan Augusto da Costa, Sampaio Jorge Luiz Mello

Abstract excerpt

Polymyxins are still used mainly in treating infections caused by carbapenem-resistant Klebsiella pneumoniae worldwide. The most frequent mechanism of acquired resistance to polymyxins in Gram-negative bacilli is the occurrence of mutations in chromosomal genes regulating operons responsible for lipopolysaccharide modification. As we observed at Santa Casa de São Paulo hospital the occurrence of infections caused...

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Identifiers

PMID: 34460074
DOI: 10.1007/s42770-021-00600-5
PMCID: PMC8578263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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