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Article

Temporal evolution of polymyxin B-resistant Klebsiella pneumoniae clones recovered from blood cultures in a teaching hospital during a 7-year period.

International journal of antimicrobial agents - 1 Mar 2018

Braun Graziela, Cayô Rodrigo, Matos Adriana Pereira, de Mello Fonseca Juliane, Gales Ana Cristina

Abstract excerpt

The polymyxins have become one of the last resorts to treat serious infections caused by KPC-2-producing Klebsiella pneumoniae worldwide. However, the increase of polymyxin consumption has favored the emergence of resistance to these compounds. In this study, we observed an increase in polymyxin B resistance rates from 0 to 30.6% among 224 K. pneumoniae isolates recovered from blood cultures between 2009 and...

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Source

Identifiers

PMID: 28887199
DOI: 10.1016/j.ijantimicag.2017.08.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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