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Article

Adaptation and Virulence of Enterovirus-A71.

Viruses - 21 Aug 2021

Kobayashi Kyousuke, Koike Satoshi

Abstract excerpt

Outbreaks of hand, foot, and mouth disease caused by enterovirus-A71 (EV-A71) can result in many deaths, due to central nervous system complications. Outbreaks with many fatalities have occurred sporadically in the Asia-Pacific region and have become a serious public health concern. It is hypothesized that virulent mutations in the EV-A71 genome cause these occasional outbreaks. Analysis of EV-A71 neurovirulence...

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Identifiers

PMID: 34452525
DOI: 10.3390/v13081661
PMCID: PMC8402912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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