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Article

Viral determinants that drive Enterovirus-A71 fitness and virulence.

Emerging microbes & infections - 1 Dec 2021

Ang Pei Yi, Chong Connie Wan Hui, Alonso Sylvie

Abstract excerpt

Hand, Foot and Mouth Disease (HFMD) is usually a self-limiting, mild childhood disease that is caused mainly by Coxsackie virus A16 (CVA16) and Enterovirus A71 (EV-A71), both members of the Picornaviridae family. However, recurring HFMD outbreaks and epidemics due to EV-A71 infection in the Western Pacific region, and the propensity of EV-A71 strains to cause severe neurological complications have made this...

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Identifiers

PMID: 33745413
DOI: 10.1080/22221751.2021.1906754
PMCID: PMC8043536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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