Article
Novel Circulating and Tissue Monocytes as Well as Macrophages in Pancreatitis and Recovery.
Gastroenterology - 1 Dec 2021
Manohar Murli, Jones Elaina K, Rubin Samuel J S, Subrahmanyam Priyanka B, Swaminathan Gayathri, Mikhail David, Bai Lawrence, Singh Gulshan, Wei Yi, Sharma Vishal, Siebert Janet C, Maecker Holden T, Husain Sohail Z, Park Walter G, Pandol Stephen J, Habtezion Aida
Abstract excerpt
BACKGROUND AND AIMS: Acute pancreatitis (AP) is an inflammatory disease with mild to severe course that is associated with local and systemic complications and significant mortality. Uncovering inflammatory pathways that lead to progression and recovery will inform ways to monitor and/or develop effective therapies. METHODS: We performed single-cell mass Cytometry by Time Of Flight (CyTOF) analysis to identify...
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