Article
Increasing sample diversity in psychiatric genetics - Introducing a new cohort of patients with schizophrenia and controls from Vietnam - Results from a pilot study.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Mar 2022
Nguyen V T, Braun A, Kraft J, Ta T M T, Panagiotaropoulou G M, Nguyen V P, Nguyen T H, Trubetskoy V, Le C T, Le T T H, Pham X T, Heuser-Collier I, Lam N H, Böge K, Hahne I M, Bajbouj M, Zierhut M M, Hahn E, Ripke S
Abstract excerpt
OBJECTIVES: Genome-Wide Association Studies (GWAS) of Schizophrenia (SCZ) have provided new biological insights; however, most cohorts are of European ancestry. As a result, derived polygenic risk scores (PRS) show decreased predictive power when applied to populations of different ancestries. We aimed to assess the feasibility of a large-scale data collection in Hanoi, Vietnam, contribute to international...
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