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Article

Identification of Transcriptional Regulators of Psoriasis from RNA-Seq Experiments.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017

Zolotarenko Alena, Chekalin Evgeny, Mehta Rohini, Baranova Ancha, Tatarinova Tatiana V, Bruskin Sergey

Abstract excerpt

Psoriasis is a common inflammatory skin disease with complex etiology and chronic progression. To provide novel insights into the molecular mechanisms of regulation of the disease we performed RNA sequencing (RNA-Seq) analysis of 14 pairs of skin samples collected from psoriatic patients. Subsequent pathway analysis and an extraction of transcriptional regulators governing psoriasis-associated pathways was...

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Source

Identifiers

PMID: 28849568
DOI: 10.1007/978-1-4939-7027-8_14

Genes

FOS
FOXA1
FOXP3
JUN
GATA3
NFATC2
NFIB
RARA
RUNX1
SRF
STAT6
TCF7
VDR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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