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Article

miR-203 promotes HaCaT cell overproliferation through targeting LXR-α and PPAR-γ

28 Jun 2020

Abstract excerpt

Psoriasis is an immune-mediated chronic inflammatory skin disease. Keratinocyte hyperproliferation has been regarded as a significant event in psoriasis pathogenesis. Considering the vital role of miRNA-mediated mRNA repression in psoriasis pathogenesis, in the present study, we attempted to investigate the mechanism of keratinocyte overproliferation from the point of miRNA-mRNA regulation. Both online microarray...

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PMID: 32594829
DOI: 10.1080/15384101.2020.1783934

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