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The impact of age on genetic risk for common diseases

26 Aug 2021

Abstract excerpt

Inherited genetic variation contributes to individual risk for many complex diseases and is increasingly being used for predictive patient stratification. Previous work has shown that genetic factors are not equally relevant to human traits across age and other contexts, though the reasons for such variation are not clear. Here, we introduce methods to infer the form of the longitudinal relationship between...

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PMID: 34437535
DOI: 10.1371/journal.pgen.1009723

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