Article
The Sex Differences in Uveal Melanoma: Potential Roles of EIF1AX, Immune Response and Redox Regulation.
Current oncology (Toronto, Ont.) - 23 Jul 2021
Liu-Smith Feng, Chiu Chi-Yang, Johnson Daniel L, Miller Phillip Winston, Glazer Evan S, Wu Zhaohui, Wilson Matthew W
Abstract excerpt
BACKGROUND: Uveal melanoma (UVM) is a rare cancer that shows sex difference in incidence and survival, with little previous report for the underlying mechanism. METHODS: This study used the SEER data (1974-2016) for an age-dependent analysis on sex difference in UVM, and further used the TCGA-UVM genomics dataset for analyzing the differential gene expression profiles in tumors from men and women. RESULTS: Our...
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