Article
Epstein-Barr virus (EBV) deletions as biomarkers of response to treatment of chronic active EBV.
British journal of haematology - 1 Oct 2021
Venturini Cristina, Houldcroft Charlotte J, Lazareva Arina, Wegner Fanny, Morfopoulou Sofia, Amrolia Persis J, Golwala Zainab, Rao Anupama, Marks Stephen D, Simmonds Jacob, Yoshikawa Tetsushi, Farrell Paul J, Cohen Jeffrey I, Worth Austen J, Breuer Judith
Abstract excerpt
Chronic active Epstein-Barr virus (CAEBV) disease is a rare condition characterised by persistent EBV infection in previously healthy individuals. Defective EBV genomes were found in East Asian patients with CAEBV. In the present study, we sequenced 14 blood EBV samples from three UK patients with CAEBV, comparing the results with saliva CAEBV samples and other conditions. We observed EBV deletions in blood, some...
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