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Article

Clinical features and whole-genome snp association study of chronic active Epstein-Barr virus infection in adults.

Virology journal - 27 Apr 2026

Mei Xuan, Yao Jie, Guan Zhen, Ao Xiu-Lan, Chen Li, Liang Ying, Zeng Zhi-Yu, Zhou Xiao-Ling, Zhou Li-Li, Wu Xia, Li Dongliang

Abstract excerpt

BACKGROUND: Adult chronic active Epstein-Barr virus infection (CAEBV) is rare, often atypical, lacks effective therapy, and has poor prognosis. Its geographic and ethnic clustering in East Asians suggests host genetic susceptibility. We aimed to define adult CAEBV clinical features and identify susceptibility SNPs and implicated genes and pathways. METHODS: Forty-six chronic EBV-infected adults and 74 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42046143
DOI: 10.1186/s12985-026-03176-4
PMCID: PMC13262204

Genes

DVL1
EGFR
ITGB1
PTEN
PTK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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