Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiomics analysis reveals the genetic and epigenetic features of high-risk NK cell–type chronic active EBV infection

30 Jul 2025

Abstract excerpt

ABSTRACT: Chronic active Epstein-Barr virus (EBV) infection (CAEBV) is an orphan disease characterized by the proliferation and infiltration of EBV-infected T/natural killer (NK) cells into multiple organs. Although CAEBV is a heterogeneous disease with diverse clinical courses, its pathogenesis remains poorly understood. In this study, we explored the molecular mechanisms underlying CAEBV by performing a...

Topics

Join the communities discussing this publication.

Immune Cell Function and Interaction
Lymphoma Diagnosis and Treatment
Viral-associated cancers and disorders

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40737598
DOI: 10.1182/blood.2024026805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiomics analysis reveals the genetic and epigenetic features of high-risk NK cell–type chronic active EBV infectionPMID 40737598Read ↗

Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphomaSemantic proximity Read ↗

Epigenomic landscape study reveals molecular subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinomaSemantic proximity Read ↗

Rapid identification and characterization of infected cells in blood during chronic active Epstein-Barr virus infection.Semantic proximity Read ↗

EBV and the Pathogenesis of NK/T Cell LymphomaSemantic proximity Read ↗

Association of Epstein-Barr virus genomic alterations with human pathologiesSemantic proximity Read ↗

Integrated Pan-Cancer Map of EBV-Associated Neoplasms Reveals Functional Host–Virus InteractionsSemantic proximity Read ↗

Nasopharyngeal Cancer: Molecular Landscape.Semantic proximity Read ↗

The Impact of Epstein-Barr Virus Infection on Epigenetic Regulation of Host Cell Gene Expression in Epithelial and Lymphocytic MalignanciesSemantic proximity Read ↗

Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escapeSemantic proximity Read ↗

Epstein-Barr Virus-Positive Cancers Show Altered B-Cell ClonalitySemantic proximity Read ↗

The EBV-Positive Tumor Methylome is Distinct from EBV-Negative in Diffuse Large B-Cell LymphomaSemantic proximity Read ↗

Methylation analysis of plasma DNA informs etiologies of Epstein-Barr virus-associated diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.