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Epstein-Barr virus (EBV) reactivation and therapeutic inhibitors

17 Jul 2019

Abstract excerpt

Epstein-Barr virus (EBV) is a ubiquitous human virus which infects almost all humans during their lifetime and following the acute phase, persists for the remainder of the life of the individual. EBV infects B lymphocytes leading to their immortalisation, with persistence of the EBV genome as an episome. In the latent phase, EBV is prevented from reactivating through efficient cytotoxic cellular immunity. EBV...

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PMID: 31315893
DOI: 10.1136/jclinpath-2019-205822

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