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Article

EphA4 receptor, overexpressed in pancreatic ductal adenocarcinoma, promotes cancer cell growth

5 Sept 2006

Abstract excerpt

To isolate novel diagnostic markers and drug targets for pancreatic ductal adenocarcinoma (PDAC), we previously performed expression profile analysis of PDAC cells using a genome-wide cDNA microarray combined with laser microdissection. Among dozens of up-regulated genes identified in PDAC cells, we herein focused on one tyrosine kinase receptor, Eph receptor A4 (EphA4), as a molecular target for PDAC therapy....

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PMID: 16965393
DOI: 10.1111/j.1349-7006.2006.00313.x

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