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Outer Membrane Vesicle Vaccine Platforms

5 Oct 2023

Abstract excerpt

Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence factor for bacteria, helping them to survive through harsh environmental conditions. Native OMVs, naturally-released from bacteria, are produced at a level too low for vaccine manufacturing, requiring chemical treatment (detergent-extracted) or genetic manipulation,...

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PMID: 37796436
DOI: 10.1007/s40259-023-00627-0

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