Article
Liver Metastatic Colorectal Tumor Cells Change Their Phenotype During Consecutive Passages on Chick Embryo Chorioallantoic Membrane: Lessons from the Lab to the Clinic.
In vivo (Athens, Greece) - 1 Jan 2000
Ceaușu Raluca Amalia, Ciolofan Alexandru, Blidișel Alexandru, Crețu Octavian Marius, Cimpean Anca Maria, Raica Marius
Abstract excerpt
BACKGROUND/AIM: Colon cancer liver metastases with desmoplastic growth pattern (dGP) have a highly heterogeneous therapy response. The aim of the study was to evaluate the dGP liver metastasis molecular profile from a chemo-naive patient by mimicking metastatic process on an experimental chick embryo chorioallantoic membrane (CAM) model. MATERIALS AND METHODS: Three successive CAM passages of dGP human colorectal...
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