Article
Sex-specific genetic factors affect the risk of early-onset periodontitis in Europeans.
Journal of clinical periodontology - 1 Nov 2021
Freitag-Wolf Sandra, Munz Matthias, Junge Olaf, Graetz Christian, Jockel-Schneider Yvonne, Staufenbiel Ingmar, Bruckmann Corinna, Lieb Wolfgang, Franke Andre, Loos Bruno G, Jepsen Søren, Dommisch Henrik, Schaefer Arne S
Abstract excerpt
AIMS: Various studies have reported that young European women are more likely to develop early-onset periodontitis compared to men. A potential explanation for the observed variations in sex and age of disease onset is the natural genetic variation within the autosomal genomes. We hypothesized that genotype-by-sex (G × S) interactions contribute to the increased prevalence and severity. MATERIALS AND METHODS:...
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