Article
Electrophysiological analysis of healthy and dystrophic 3-D bioengineered skeletal muscle tissues.
American journal of physiology. Cell physiology - 1 Oct 2021
Nguyen Christine T, Ebrahimi Majid, Gilbert Penney M, Stewart Bryan A
Abstract excerpt
Recently, methods for creating three-dimensional (3-D) human skeletal muscle tissues from myogenic cell lines have been reported. Bioengineered muscle tissues are contractile and respond to electrical and chemical stimulation. In this study, we provide an electrophysiological analysis of healthy and dystrophic 3-D bioengineered skeletal muscle tissues, focusing on Duchenne muscular dystrophy (DMD). We enlist the...
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