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Article

Focus on the road to modelling cardiomyopathy in muscular dystrophy

7 Jul 2021

Abstract excerpt

Alterations in the DMD gene, which codes for the protein dystrophin, cause forms of dystrophinopathies such as Duchenne muscular dystrophy, an X-linked disease. Cardiomyopathy linked to DMD mutations is becoming the leading cause of death in patients with dystrophinopathy. Since phenotypic pathophysiological mechanisms are not fully understood, the improvement and development of new disease models, considering...

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PMID: 34254111
DOI: 10.1093/cvr/cvab232

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