Article
A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans.
Yonsei medical journal - 1 Sept 2017
Hong Eun Pyo, Jeon Jin Pyeong, Kim Sung Eun, Yang Jin Seo, Choi Hyuk Jai, Kang Suk Hyung, Cho Yong Jun
Abstract excerpt
PURPOSE: Lysyl oxidase (LOX) controls the cross-linking and maturation of elastin and collagen fibers. In this study, we investigated the association between LOX gene polymorphisms and intracranial aneurysm (IA) formation in a homogeneous Korean population. MATERIALS AND METHODS: This cross-sectional study involved 80 age-sex matched patients with IA and controls. Fisher's exact test was performed to analyze...
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