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Article

TMB and Inflammatory Gene Expression Associated with Clinical Outcomes following Immunotherapy in Advanced Melanoma.

Cancer immunology research - 1 Oct 2021

Hodi F Stephen, Wolchok Jedd D, Schadendorf Dirk, Larkin James, Long Georgina V, Qian Xiaozhong, Saci Abdel, Young Tina C, Srinivasan Sujaya, Chang Han, Tang Hao, Wind-Rotolo Megan, Rizzo Jasmine I, Jackson Donald G, Ascierto Paolo A

Abstract excerpt

Outcomes for patients with melanoma have improved over the past decade as a result of the development and FDA approval of immunotherapies targeting cytotoxic T lymphocyte antigen-4 (CTLA-4), programmed death-1 (PD-1), and programmed death ligand 1 (PD-L1). However, these therapies do not benefit all patients, and an area of intensive research investigation is identifying biomarkers that can predict which patients...

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Identifiers

PMID: 34389558
DOI: 10.1158/2326-6066.CIR-20-0983
PMCID: PMC9414280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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