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Article

iBRET Screen of the ABCD1 Peroxisomal Network and Mutation-Induced Network Perturbations.

Journal of proteome research - 3 Sept 2021

Lotz-Havla Amelie S, Woidy Mathias, Guder Philipp, Friedel Caroline C, Klingbeil Julian M, Bulau Ana-Maria, Schultze Anja, Dahmen Ilona, Noll-Puchta Heidi, Kemp Stephan, Erdmann Ralf, Zimmer Ralf, Muntau Ania C, Gersting Søren W

Abstract excerpt

Mapping the network of proteins provides a powerful means to investigate the function of disease genes and to unravel the molecular basis of phenotypes. We present an automated informatics-aided and bioluminescence resonance energy transfer-based approach (iBRET) enabling high-confidence detection of protein-protein interactions in living mammalian cells. A screen of the ABCD1 protein, which is affected in...

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PMID: 34383492
DOI: 10.1021/acs.jproteome.1c00330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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