Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extremely lethal and hypervirulent Mycobacterium tuberculosis strain cluster emerging in Far East, Russia.

Emerging microbes & infections - 1 Dec 2021

Vinogradova Tatiana, Dogonadze Marine, Zabolotnykh Natalia, Badleeva Maria, Yarusova Irina, Vyazovaya Anna, Gerasimova Alena, Zhdanova Svetlana, Vitovskaya Maria, Solovieva Natalia, Pasechnik Oksana, Ogarkov Oleg, Mokrousov Igor

Abstract excerpt

Mycobacterium tuberculosis strains of the early ancient sublineage of the Beijing genotype are mostly drug susceptible and mainly circulate in East Asia. We have recently discovered two clusters of this sublineage emerging in the Asian part of Russia (VNTR-defined 1071-32 and 14717-15 types) and, to our surprise, both were strongly MDR/XDR-associated. Here, we evaluated their pathogenic features. The clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antitubercular Agents
Share to Beijing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Multiple, Bacterial

Share to Epidemics

Share to Mycobacterium tuberculosis

Share to Russia

Share to Tuberculosis, Multidrug-Resistant

Share to Virulence

Source

Open in PubMed Open full text

Identifiers

PMID: 34380361
DOI: 10.1080/22221751.2021.1967704
PMCID: PMC8381949

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extremely lethal and hypervirulent Mycobacterium tuberculosis strain cluster emerging in Far East, Russia.PMID 34380361Read ↗

Impact of pathobiological diversity of Mycobacterium tuberculosis on clinical features and lethal outcome of tuberculosis.Semantic proximity Read ↗

Practical approach to detection and surveillance of emerging highly resistant Mycobacterium tuberculosis Beijing 1071-32-cluster.Semantic proximity Read ↗

Insight into pathogenomics and phylogeography of hypervirulent and highly-lethal Mycobacterium tuberculosis strain cluster.Semantic proximity Read ↗

Increased transmissibility of Russian successful strain Beijing B0/W148 of Mycobacterium tuberculosis: Indirect clues from history and demographics.Semantic proximity Read ↗

Increasing circulation of multi-drug resistant tuberculosis strains in Buryatia, high-burden and ethnically diverse region in the Russian Far East.Semantic proximity Read ↗

Genetic Diversity and Primary Drug Resistance of Mycobacterium tuberculosis Beijing Genotype Strains in Northwestern RussiaSemantic proximity Read ↗

Mycobacterium tuberculosis strains of the modern sublineage of the Beijing family are more likely to display increased virulence than strains of the ancient sublineage.Semantic proximity Read ↗

Key impact of Beijing strains including new resistant clusters on spread of multidrug-resistant tuberculosis in northern Russia.Semantic proximity Read ↗

Genomic signatures of drug resistance in highly resistant Mycobacterium tuberculosis strains of the early ancient sublineage of Beijing genotype in Russia.Semantic proximity Read ↗

Tuberculous spondylitis in Russia and prominent role of multidrug-resistant clone Mycobacterium tuberculosis Beijing B0/W148.Semantic proximity Read ↗

Genetic diversity of the Mycobacterium tuberculosis Beijing family in Brazil and Mozambique and relation with infectivity and induction of necrosis in THP-1 cells.Semantic proximity Read ↗

Emerging multidrug resistant Mycobacterium tuberculosis strains of the Beijing genotype circulating in Russia express a pattern of biological properties associated with enhanced virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.