Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced mixture interpretation with macrohaplotypes based on long-read DNA sequencing.

International journal of legal medicine - 1 Nov 2021

Ge Jianye, King Jonathan, Mandape Sammed, Budowle Bruce

Abstract excerpt

Deconvoluting mixture samples is one of the most challenging problems confronting DNA forensic laboratories. Efforts have been made to provide solutions regarding mixture interpretation. The probabilistic interpretation of Short Tandem Repeat (STR) profiles has increased the number of complex mixtures that can be analyzed. A portion of complex mixture profiles, particularly for mixtures with a high number of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA Fingerprinting
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Microsatellite Repeats

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 34378071
DOI: 10.1007/s00414-021-02679-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced mixture interpretation with macrohaplotypes based on long-read DNA sequencing.PMID 34378071Read ↗

Identification and sequencing of 59 highly polymorphic microhaplotypes for analysis of DNA mixtures.Semantic proximity Read ↗

SMART-MHmix: A probabilistic model for microhaplotype-based forensic DNA mixture analysis.Semantic proximity Read ↗

Evaluation of the Microhaplotypes panel for DNA mixture analyses.Semantic proximity Read ↗

A sequence-based 74plex microhaplotype assay for analysis of forensic DNA mixtures.Semantic proximity Read ↗

Performance comparison of a previously validated microhaplotype panel and a forensic STR panel for DNA mixture analysis.Semantic proximity Read ↗

Applications of Probabilistic Genotyping Method for Combining Evidence Across Microhaplotype DNA Mixture Profiles.Semantic proximity Read ↗

Screening of highly discriminative microhaplotype markers for individual identification and mixture deconvolution in East Asian populations.Semantic proximity Read ↗

A 124-plex Microhaplotype Panel Based on Next-generation Sequencing Developed for Forensic Applications.Semantic proximity Read ↗

A multipurpose panel of microhaplotypes for use with STR markers in casework.Semantic proximity Read ↗

Microhaplotype and Y-SNP/STR (MY): A novel MPS-based system for genotype pattern recognition in two-person DNA mixtures.Semantic proximity Read ↗

Improving DNA mixtures analysis using compound markers composed of InDels and SNPs screened from the whole genome with next-generation sequencing.Semantic proximity Read ↗

Evaluating 130 microhaplotypes across a global set of 83 populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.