Article
Improving DNA mixtures analysis using compound markers composed of InDels and SNPs screened from the whole genome with next-generation sequencing.
Electrophoresis - 1 Mar 2024
Tan Mengyu, Xue Jiaming, Wu Qiushuo, Zheng Yazi, Liu Guihong, Zhang Ranran, Wu Mengna, Song Jinlong, Xiao Yuanyuan, Chen Dezhi, Lv Meili, Liao Miao, Qu Shengqiu, Liang Weibo
Abstract excerpt
Next-generation sequencing (NGS) allows for better identification of insertion and deletion polymorphisms (InDels) and their combination with adjacent single nucleotide polymorphisms (SNPs) to form compound markers. These markers can improve the polymorphism of microhaplotypes (MHs) within the same length range, and thus, boost the efficiency of DNA mixture analysis. In this study, we screened InDels and SNPs...
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