Article
Performance comparison of a previously validated microhaplotype panel and a forensic STR panel for DNA mixture analysis.
Forensic science international. Genetics - 1 Jan 2025
González-Bao J, Mosquera-Miguel A, Casanova-Adán L, Ambroa-Conde A, Ruiz-Ramírez J, Cabrejas-Olalla A, Boullón-Cassau M, Freire-Aradas A, Rodríguez-López A, Roth C, Lagacé R, Phillips C, Lareu M V, de la Puente M
Abstract excerpt
Short Tandem Repeats (STRs) are the most widespread markers in forensic genetics. However, STR stutter peaks can mask alleles from a minor contributor when analysing mixtures, hindering the interpretation of complex profiles. In this study we compared the performance of a previously described panel of microhaplotypes (MHs), an alternative type of forensic marker, against a standard STR kit. The parameters...
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