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Article

A continuous model for interpreting microhaplotype profiles of forensic DNA mixtures.

Forensic science international. Genetics - 1 Jun 2025

Wang Yuting, Hou Tingyun, Zhu Qiang, Hu Yuhan, Wang Haoyu, Wei Yifan, Wang Yufang, Zhang Ji

Abstract excerpt

Microhaplotypes (MHs) have great potential in forensic DNA analysis, with applications in individual identification, kinship analysis and ancestry inference. No matter the forensic application, the analysis of DNA mixtures may be encountered. This study aims to develop and evaluate a continuous model for interpreting mixed genotype data from MH markers. We characterized MH profile features and modeled allele read...

Read the complete abstract on PubMed

Topics

Humans
Haplotypes
Likelihood Functions
DNA Fingerprinting
DNA
Models, Genetic
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Forensic Genetics

Polymorphism, Single Nucleotide

Alleles

Gene Frequency

Source

Identifiers

PMID: 40121764
DOI: 10.1016/j.fsigen.2025.103271

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