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WD40 repeat 43 mediates cell survival, proliferation, migration and invasion via vimentin in colorectal cancer

9 Aug 2021

Abstract excerpt

BACKGROUND: WD40 repeat (WDR)43 is an RNA-binding protein that belongs to the WDR domain protein family. Its biological function is largely unclear, particularly in colorectal cancer (CRC). METHODS: In the present study, we searched the TCGA database and found the correlation between WDR43 and CRC. Subsequently, the high expression of WDR43 in human clinical samples of CRC was validated and we further examined...

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PMID: 34372874
DOI: 10.1186/s12935-021-02109-1

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