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MicroRNA-17-5p regulates EMT by targeting vimentin in colorectal cancer

16 Jun 2020

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transition (EMT) is the most common cause of death in colorectal cancer (CRC). In this study, we investigated the functional roles of miRNA-17-5p in EMT of CRC cells. METHODS: In order to determine if miRNA-17-5p regulated EMT, the precursors and inhibitors of miR-17-5p were transduced into four CRC cells. To evaluate the regulatory mechanism, we performed argonaute 2 (Ago2)...

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PMID: 32546833
DOI: 10.1038/s41416-020-0940-5

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