Article
Reversing effect of ring finger protein 43 inhibition on malignant phenotypes of human hepatocellular carcinoma.
Molecular cancer therapeutics - 1 Jan 2013
Xing Chunyang, Zhou Wuhua, Ding Songming, Xie Haiyang, Zhang Wu, Yang Zhe, Wei Bajin, Chen Kangjie, Su Rong, Cheng Jun, Zheng Shusen, Zhou Lin
Abstract excerpt
It has been shown that Ring finger protein 43 (RNF43) is overexpressed in colorectal cancer and mediates cancer cell proliferation; however, its role in hepatocellular carcinoma (HCC) remains unknown. In this study, we found that RNF43 was frequently overexpressed in HCCs, and this overexpression...
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