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Article

NK-92 cells change their phenotype and function when cocultured with IL-15, IL-18 and trophoblast cells.

Immunobiology - 1 Sept 2021

Mikhailova Valentina, Khokhlova Evgeniia, Grebenkina Polina, Salloum Zeina, Nikolaenkov Igor, Markova Kseniya, Davidova Alina, Selkov Sergey, Sokolov Dmitriy

Abstract excerpt

NK cell development is affected by their cellular microenvironment and cytokines, including IL-15 and IL-18. NK cells can differentiate in secondary lymphoid organs, liver and within the uterus in close contact with trophoblast cells. The aim was to evaluate changes in the NK cell phenotype and function in the presence of IL-15, IL-18 and JEG-3, a trophoblast cell line. When cocultured with JEG-3 cells, IL-15...

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Identifiers

PMID: 34365089
DOI: 10.1016/j.imbio.2021.152125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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