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Article

Human dNK cell function is differentially regulated by extrinsic cellular engagement and intrinsic activating receptors in first and second trimester pregnancy.

Cellular & molecular immunology - 1 Feb 2017

Zhang Jianhong, Dunk Caroline E, Kwan Melissa, Jones Rebecca L, Harris Lynda K, Keating Sarah, Lye Stephen J

Abstract excerpt

Decidual natural killer (dNK) cells express an array of activation receptors to regulate placental immunity and development during early pregnancy. We investigated the functional character of human dNK cells during the first and second trimester of gestation and the interaction between dNK and trophoblast cells. Although the frequency of CD56+CD16- dNK among the total CD45+ leukocytes did not change over this...

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Source

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Identifiers

PMID: 26277900
DOI: 10.1038/cmi.2015.66
PMCID: PMC5301153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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