Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells.

doi:10.1016/j.jmb.2021.167184

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Article

Schizophrenia risk candidate protein ZNF804A interacts with STAT2 and influences interferon-mediated gene transcription in mammalian cells.

Journal of molecular biology - 17 Sept 2021

Klockmeier Konrad, Silva Ramos Eduardo, Raskó Tamás, Martí Pastor Adrián, Wanker Erich E

Abstract excerpt

Previously evidence was presented that the single-nucleotide polymorphism rs1344706 located in an intronic region of the ZNF804A gene is associated with reduced transcript levels in fetal brains. This genetic variation in the gene encoding the zinc-finger protein ZNF804A is associated with schizophrenia (SZ) and bipolar disorder. Currently, the molecular and cellular function of ZNF804A is unclear. Here, we...

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PMID: 34364876
DOI: 10.1016/j.jmb.2021.167184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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