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Article

[Effect of FLT3-ITD Length on 32D Cell Proliferation, Apoptosis and Sensitivity to FLT3 Inhibitor].

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2021

Liu Song-Bai, Dong Hao-Jie, Wang Jun, Qiu Qiao-Cheng, Xue Sheng-Li, Li Ling

Abstract excerpt

OBJECTIVE: To study the effects of FLT3-ITD length on 32D cell proliferation, apoptosis and sensitivity to FLT3 inhibitor, so as to provide references for stepwise therapy of FLT3-ITD mutated acute myeloid leukemia patients. METHODS: Three different FLT3-ITD mutants with same or adjacent insert sites were selected and constructed in an eukaryotic expression vector. FLT3-ITD mutants stably expressed 32D cell...

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Source

Identifiers

PMID: 34362479
DOI: 10.19746/j.cnki.issn.1009-2137.2021.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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