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Article

The Role of PERK in Understanding Development of Neurodegenerative Diseases.

International journal of molecular sciences - 29 Jul 2021

Smedley Garrett Dalton, Walker Keenan E, Yuan Shauna H

Abstract excerpt

Neurodegenerative diseases are an ever-increasing problem for the rapidly aging population. Despite this, our understanding of how these neurodegenerative diseases develop and progress, is in most cases, rudimentary. Protein kinase RNA (PKR)-like ER kinase (PERK) comprises one of three unfolded protein response pathways in which cells attempt to manage cellular stress. However, because of its role in the cellular...

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Identifiers

PMID: 34360909
DOI: 10.3390/ijms22158146
PMCID: PMC8348817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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