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Article

Deleterious single nucleotide polymorphisms (SNPs) of human IFNAR2 gene facilitate COVID-19 severity in patients: a comprehensive in silico approach.

Journal of biomolecular structure & dynamics - 1 Jan 2022

Akter Shamima, Roy Arpita Singha, Tonmoy Mahafujul Islam Quadery, Islam Md Sajedul

Abstract excerpt

In humans, the dimeric receptor complex IFNAR2-IFNAR1 accelerates cellular response triggered by type I interferon (IFN) family proteins in response to viral infection including Coronavirus infection. Studies have revealed the association of the IFNAR2 gene with severe illness in Coronavirus infection and indicated the association of genomic variants, i.e. single nucleotide polymorphisms (SNPs). However,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34355676
DOI: 10.1080/07391102.2021.1957714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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