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Predicting human and viral protein variants affecting COVID-19 susceptibility and repurposing therapeutics.

Scientific reports - 20 Jun 2024

Waman Vaishali P, Ashford Paul, Lam Su Datt, Sen Neeladri, Abbasian Mahnaz, Woodridge Laurel, Goldtzvik Yonathan, Bordin Nicola, Wu Jiaxin, Sillitoe Ian, Orengo Christine A

Abstract excerpt

The COVID-19 disease is an ongoing global health concern. Although vaccination provides some protection, people are still susceptible to re-infection. Ostensibly, certain populations or clinical groups may be more vulnerable. Factors causing these differences are unclear and whilst socioeconomic and cultural differences are likely to be important, human genetic factors could influence susceptibility. Experimental...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38902252
DOI: 10.1038/s41598-024-61541-1
PMCID: PMC11190248

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