Article
Next-Generation Sequencing Reveals Novel Genetic Variants for Dilated Cardiomyopathy in Pediatric Chinese Patients.
Pediatric cardiology - 1 Jan 2022
Wang Yan, Han Bo, Fan Youfei, Yi Yingchun, Lv Jianli, Wang Jing, Yang Xiaofei, Jiang Diandong, Zhao Lijian, Zhang Jianjun, Yuan Hui
Abstract excerpt
Dilated cardiomyopathy (DCM) is a myocardial disease characterized by bilateral or left ventricular cardiac dilation and systolic dysfunction that can lead to heart failure and sudden cardiac death in children. Many studies have focused on genetic variation in DCM-related genes in adult populations; however, the mutational landscape in pediatric DCM patients remains undetermined, especially in the Chinese...
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