Article
Molecular analysis of inherited cardiomyopathy using next generation semiconductor sequencing technologies.
Journal of translational medicine - 30 Aug 2018
Lu Chaoxia, Wu Wei, Liu Fang, Yang Kunqi, Li Jiacheng, Liu Yaping, Wang Rongrong, Si Nuo, Gao Peng, Liu Yongtai, Zhang Shuyang, Zhang Xue
Abstract excerpt
BACKGROUND: Cardiomyopathies are the most common clinical and genetic heterogeneity cardiac diseases, and genetic contribution in particular plays a major role in patients with primary cardiomyopathies. The aim of this study is to investigate cases of inherited cardiomyopathy (IC) for potential disease-causing mutations in 64 genes reported to be associated with IC. METHODS: A total of 110 independent cases or...
Topics
- Adenine Nucleotide Translocator 1
- Adult
- Arrhythmogenic Right Ventricular Dysplasia
- Cardiac Myosins
- Cardiomyopathies
- Cardiomyopathy, Dilated
- Cardiomyopathy, Hypertrophic
- Cardiomyopathy, Restrictive
- Carrier Proteins